Anton Wierix II (born Antwerp, c. 1555–9; buried Antwerp, March 11, 1604) was a Flemish engraver, brother of Jan Wierix. He was probably taught by Jan. By 1579, he had engraved two plates for a series of four satirical prints, published by Willem van Haecht; the other two were by Jerome Wierix. This is the earliest of many examples of collaboration between the two brothers. In 1587, Anton went into a short-lived partnership (of only three months) with Hans Liefrinck, and in 1590–91, he became a master. This coincided with his October 4, 1590 marriage to Catharina, daughter of the glass painter Gummarus van den Driessche; like Jerome's, this marriage produced one son and four daughters. Anton II was also frequently in difficulties over debts, sometimes pawning his copperplates. His work includes a great number of religious scenes, some designed by himself, others after work by such artists as Marten de Vos and Crispin van den Broeck. After Anton’s early death, Jerome took over his copperplates and published several of Anton’s engravings under his own name. The work of his son, Anton Wierix III, has often been confused with that of the father.

See also the Wierix family, Jan Wierix, and Jerome Wierix.